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Drug prophylaxis in reducing postoperative complications of tonsillectomy

Comparison of Dexmedetomidine and Ketamine in Postoperative complications in ChildrenUndergoing Tonsillectomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210712051848N2
Enrollment
87
Registered
2021-10-17
Start date
2018-12-22
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of anesthesia and surgery of pediatric tonsillectomy.

Interventions

Intervention 1: Intervention group: Group 1 received 20 cc normal saline containing dexmedetomidine (1 µg./kg) administered for 10 minutes. Intervention 2: Intervention group: Group 2 received 20 cc

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 13 Years

Inclusion criteria

Inclusion criteria: Age between 2 to 13 years Tonsillectomy surgery with or without adenoidectomy Class 1 of American Society of Anesthesiologists classification, include: A normal healthy patient without acute or chronic disease and normal body mass index percentile for age Class 2 of American Society of Anesthesiologists classification, include: A patient with mild systemic disease such as: asymptomatic congenital cardiac disease, well controlled epilepsy, non-insulin dependent diabetes mellitus and abnormal body mass index percentile for age

Exclusion criteria

Exclusion criteria: Neurological defects Organ failure drug sensitivity

Design outcomes

Primary

MeasureTime frame
Postoperative pain. Timepoint: For 2 hours after surgery at 30 minute intervals. Method of measurement: Pain ;modified CHOPES.;?Emergence delirium. Timepoint: For 2 hours after surgery at 30 minute intervals. Method of measurement: Emergence delirium; WATCHA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMalihe Khayat Kashani

Tehran University of Medical Sciences

malihekashany@yahoo.com+98 21 6443 2592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026