Effect of pentoxifylline in treatment of patients with slow flow coronary arteries

Evaluation of the effect of oral pentoxifylline on reducing chest pain in ischemic patients with slow flow coronary arteries

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210711051842N1

Enrollment

Registered

2022-04-30

Start date

2022-04-09

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pentoxifylline in patients with slow flow coronary arteries.

Interventions

Intervention group: patients with slow flow coronary arteries in angiography will be treated with standard medicine for two weeks and in case of pain continuation, will be treated with oral pentoxifyl

Eligibility

Sex/Gender

All

Age

30 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with slow flow coronary arteries in angiography

Exclusion criteria

Exclusion criteria: Age more than thirty years Creatinine clearance less than 30 Severe aortic stenosis Severe mitral stenosis

Design outcomes

Primary

Measure	Time frame
Severity of chest pain through Likert scale. Timepoint: Evaluation of chest pain after angiography and after two weeks and one month. Method of measurement: Questionnarie for evaluating severity,frequency and duration of chest pain.	—

Secondary

Measure	Time frame
Frequency chest pain. Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage.;Duration of chest pain. Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage.;Severity of chest pain based on Canadian cardiovascular society score (CCS). Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage.	—

Measure

Time frame

Frequency chest pain. Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage.;Duration of chest pain. Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage.;Severity of chest pain based on Canadian cardiovascular society score (CCS). Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Teimouri Dastjerdan

Mashhad University of Medical Sciences

teimouridr971@mums.ac.ir+98 51 3867 9747

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026