Acute Respiratory Distress Syndrome. Acute respiratory distress syndrome
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, patients received a suspension prepared from pentoxifylline tablets at a dose of 400mg/day in three divided doses for one week. Intervent
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 65 years Trauma patients at risk for ARDS who have lips=4 based on lung injury prediction score (lips)
Exclusion criteria
Exclusion criteria: Not having written informed consent. Patients with adrenal insufficiency. Patients with inflammation of the blood vessels. Patients with intolerance to methylxanthine and pentoxifylline. Patients who can not be prescribed the drug orally. Occurrence of possible drug-related side effects if dangerous or intolerable to the patient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of acute respiratory distress syndrome. Timepoint: During the study and at the end of the study. Method of measurement: Diagnosis based on criteria for diagnosing acute respiratory distress syndrome.;Respiration rate. Timepoint: At baseline and during the receive of the medication. Method of measurement: Cardiac Monitoring.;Heart rate. Timepoint: At baseline and during the receive of the medication. Method of measurement: Cardiac Monitoring.;Continuous pulse oximetry. Timepoint: At baseline and during the receive of the medication. Method of measurement: Capnography.;Blood pressure. Timepoint: At baseline and during the receive of the medication. Method of measurement: Cardiac Monitoring.;Blood gas factors. Timepoint: At baseline and during the receive of the medication. Method of measurement: Capnography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahid Jomehzadeh
Mashhad University of Medical Sciences
Outcome results
None listed