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Effect of probiotics in the therapy of Pediatrics Burn

Effect of probiotics in the therapy of Pediatrics thermal Burn: A prospective double- blind, controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210708051822N1
Enrollment
100
Registered
2021-08-02
Start date
2021-08-23
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thermal Burn in children. Burn and corrosion

Interventions

Intervention 1: Intervention group: Probiotic supply group that will receive oral package including 1- lactobacillus rhamnosus 2- lactobacillus rotteri 3- lactobacillus acidophilus 4-lactobacillusbulg

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children between 1-15 years old Burn with total body surface area 10-50% Burn with deep area between 5-10%

Exclusion criteria

Exclusion criteria: Children with chronic GI diseases Children with chronic diseases for example diabetes Children with upper respiratory tract or inhalation injury Children with hereditary and congenital immune system disorders children with chemical and electrical burn

Design outcomes

Primary

MeasureTime frame
The rate of infection in thermal burn of children. Timepoint: Zero (admission day), 4, 7 and 14 day and until one year after hospitalization. Method of measurement: To calculate the number of positive culture reported by laboratory in thermal burn of children according to patients file.;The length of hospital stay in thermal burn of children. Timepoint: Time of discharge or death. Method of measurement: To calculate the length of hospital stay on the time of discharge or death according to patients file.;The need to skin graft in thermal burn of children. Timepoint: From discharge until one year. Method of measurement: To calculate the number of skin graft from discharge until one year according to patients file.;Mortality due to thermal burn of children. Timepoint: From hospitalization until one year. Method of measurement: The mortality rate ( the proportion of death to number of hospitalized patients) in thermal burn of children.

Secondary

MeasureTime frame
Length of hospital stay. Timepoint: Date of discharge and one year after burn. Method of measurement: Number of hospitalized days.;The need to skin graft. Timepoint: From discharge until one year after burn. Method of measurement: The number of skin grafts.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Masoumi Asl

Iran University of Medical Sciences

masoumiasl.h@iums.ac.ir+98 21 4438 0119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026