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The effect of acetazolamide on respiratory parameters of mechanically ventilated patients

Evaluating the effect of adding acetazolamide to routine regimen on respiratory parameters of mechanically ventilated patients in the intensive care unit

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210707051809N1
Enrollment
30
Registered
2022-07-18
Start date
2022-08-23
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients connected to a ventilator.

Interventions

Intervention 1: Intervention group: Patients connected to a ventilator who, in addition to routine care, take acetazolamide tablets. Acetazolamide 250 mg tablets are administered orally (gavage) twice

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients should be connected to a ventilator Patients diagnosed with non-traumatic illness (absence of trauma, especially head and chest trauma) Age over 18 years old

Exclusion criteria

Exclusion criteria: Hemodynamic instability (patients during heart shock and severe cardiovascular disorders, patients with brain death, patients in need of pacemakers, patients with renal failure, etc.) Presence of metabolic acidosis in the ABG test

Design outcomes

Primary

MeasureTime frame
Respiratory rate. Timepoint: Four times a day (morning, once before and once after) - (evening, once before and once after) and for 3 consecutive days. Method of measurement: Cardiopulmonary monitoring device and ventilator device.;Tidal volume. Timepoint: Four times a day (morning, once before and once after) - (evening, once before and once after) and for 3 consecutive days. Method of measurement: Cardiopulmonary monitoring device and ventilator device.;Percentage of hemoglobin saturated with oxygen. Timepoint: Four times a day (morning, once before and once after) - (evening, once before and once after) and for 3 consecutive days. Method of measurement: Cardiopulmonary monitoring device and ventilator device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehnam Esbakian Bandpey

Babol University of Medical Sciences

BEHNAM.ESBAKIAN@GMAIL.COM+98 11 3219 9592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026