Condition 1: Colorectal Cancer. Condition 2: Colorectal Cancer. Malignant neoplasm of colon Malignant neoplasm of rectum
Conditions
Interventions
Intervention 1: Intervention group: 1-Patients will take two capsules (daily) containing several probiotic strains from one week before the start of treatment until 10 days after the end of radiothera
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Adults with colorectal cancer who are candidates for radiotherapy as part of their treatment
Exclusion criteria
Exclusion criteria: Consumption of narcotic painkillers Existence of acute and chronic gastrointestinal complications before starting treatment Take any antibiotics one week before the start to end of radiotherapy Received radiation therapy in the abdomen and pelvis in recent years Use probiotic supplements during the 15 days before the study and also take other probiotic forms including probiotic yogurt and other fermented foods
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: Questionnaire.;Gastrointestinal disorders. Timepoint: At the beginning of the study and 6 months after the intervention. Method of measurement: Clinical examination by an oncologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Thrombocytopenia-Leukopenia-Anemia. Timepoint: At the beginning of the study and 8 weeks after the intervention. Method of measurement: CBC Test(Complete blood count). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Jamali
Shiraz University of Medical Sciences
Outcome results
None listed