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Assessment of effect of Tranexamic acid on hemorrhage reduction in hysterectomy

Assessment of effect of intravenus tranexamic acid on hemorrhage reduction during and after hysteretomy in comparison with control group

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210703051769N1
Enrollment
60
Registered
2021-08-22
Start date
2016-08-22
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Hysterectomy. Condition 2: Blood transfusion. Condition 3: Tranexamic acid. Acquired absence of both cervix and uterus

Interventions

Intervention 1: Intervention group: recieve 1 gr tranexamic acid as slow intravenus bolus.Tranexamic injection was prepared by diluting 1 gr (10ml) tranexamic acid with 20 ml of5% glucose. Interventio

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Candidate of vaginal or abdominal hystrectomy Between 35-70 years old American society of anesthesiologist (ASA) grade for physical status 1 or 2

Exclusion criteria

Exclusion criteria: Anemia Hepatic dysfunction Renal dysfunction Serious cardiac disease Serious respiratory disease Acquired or congenital coagulopathy Previous history of deep venus thrombosis or thromboembolic disease ASA more than 2 Sensitive to tranexamicacid

Design outcomes

Primary

MeasureTime frame
Blood loss. Timepoint: During and after sugery. Method of measurement: During the surgery by weighting swabs,spinges,operative drapes and measuring the volume in suction buttles after surgery by measuring the drain collectors in post anesthesia care unit.;Blood transfusion. Timepoint: During and 12 hours after surgery. Method of measurement: Pack cell.

Secondary

MeasureTime frame
Hemoglobin. Timepoint: During and 12 hours after surgery. Method of measurement: Blood test.;Hematocrit. Timepoint: Before and 12 hours after surgery. Method of measurement: Blood test.;Operation time. Timepoint: Operation time. Method of measurement: Timer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEnsiyeh Bahadoran

Qazvin University of Medical Sciences

Bahadoran.ensiyeh@yahoo.com+98 28 3333 0923

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026