Mild to moderate Alzheimer's. Alzheimer's disease
Conditions
Interventions
Intervention 1: Intervention group: 3 packs of 30 oral herbal capsules of 500 mg (Boswellia as the main component about 160 mg, physalis or puppet behind the curtain, cinnamon and peppermint 14 mg eac
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: people over 50 years old who have been diagnosed with mild to moderate Alzheimer's disease based on a clinical interview with a DSM-V neurologist Minimum primary education
Exclusion criteria
Exclusion criteria: Major psychiatric disorders such as depression, schizophrenia; psychotic disorders Other causes of dementia include pure vascular dementia, airway dementia, and frontotemporal dementia. Treatable causes of dementia such as metabolic disorders Patients with severe hepatic impairment (Child-Pugh class c), renal (GFR <25 ml / min) and cardiac (EF <15%) Taking the drug memantine Taking any medication or herbal supplement with an effect on cognitive function Reluctance to continue the plan, at any time and for any reason during the study Serious side effects during treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of cognitive disorders in MMSE, MOCA questionnaires. Timepoint: 3 months from the start of the study. Method of measurement: MMSE(Mini–mental state examination), MOCA(montreal cognitive assessment).;Behavioral Disorders Score in NPI Questionnaire. Timepoint: 3 months from the start of the study. Method of measurement: (Neuropsychiatric Inventor)NPI test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigation of side effects. Timepoint: monthly. Method of measurement: Ask questions of the patient and record information. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahsa Panahishokouh
Tehran University of Medical Sciences
Outcome results
None listed