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Effect of a cognitive intervention with pain education in improvement of knee osteoarthritis

Comparing the influence of pain education and behavioral graded activity with placebo education and behavioral graded activity on pain-related outcomes, central sensitization, function, and psychological factors in individuals with knee osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210701051754N3
Enrollment
160
Registered
2023-03-12
Start date
2023-04-21
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: People in this group do 3 to 6 sessions of pain education and about 19 sessions during 55 weeks of graded behavioral activities. Pain education includes individual

Sponsors

Kharazmi University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to No maximum

Inclusion criteria

Inclusion criteria: Being Persian-native speaker male and female Being above 45 years old Having primary complaint of knee pain diagnosed as knee OA (>3 months’ duration) by an orthopedic physician

Exclusion criteria

Exclusion criteria: Having self-reported knee replacement or any other lower limb surgery 6 months prior to participation Having a history of inflammatory, metabolic or neurological disease Having knee ligament or meniscus injury in previous year Having any mental health conditions Using therapeutic modalities 6 months before participation.

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: Before the intervention, week 13, and week 55. Method of measurement: Using Persian translated of McGill pain questionnaire as well as numeric rating scale.

Secondary

MeasureTime frame
Movement evoke pain. Timepoint: Before the intervention, week 13, and week 55. Method of measurement: Using a 10 cm numeric pain rating scale during standing balance, walking 4 meters at normal speed, and performing 5 repetitions of standing up from a chair.;Pressure pain threshold at pain location and far from pain location. Timepoint: Before the intervention, week 13, and week 55. Method of measurement: Using a manual pressure algometer with a speed of 40 kPa/s.;Central sensitization. Timepoint: Before the intervention, week 13, and week 55. Method of measurement: Using Persian translated of Central sensitization intervery.;Function. Timepoint: Before the intervention, week 13, and week 55. Method of measurement: Using 3 tests, standing balance time, walking time of 4 meters at normal speed, and time of standing up from a chair for 5 repetitions.;Pain Catastrophizing. Timepoint: Before the intervention, week 13, and week 55. Method of measurement: Using Persian translated of Pain Catastrophizing Scale.;Kinesiophobia. Timepoint: Before the intervention, week 13, and week 55. Method of measurement: Using Persian translated of Tampa scale of kinesiophobia.;Illness Perception. Timepoint: Before the intervention, week 13, and week 55. Method of measurement: Using Persian translated of Brief Illness Perception Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Letafatkar

Kharazmi University

letafatkaramir@yahoo.com+98 21 2222 8001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026