Rheumatoid arthritis. Rheumatoid arthritis with rheumatoid factor
Conditions
Interventions
Intervention 1: Intervention group: 500 milligram capsule of sea buckthorn extract, once daily, up to 90 days, manufactured in School of Persian and complementary medicine of Mashhad university of med
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Newly diagnosed patient based on ACR/EULAER criteria for rheumatoid arthritis. Patient who has received no medication for rheumatoid arthritis until now. Disease severity should be between 2.5 to 5.5 based on DAS criteria.
Exclusion criteria
Exclusion criteria: Patient MI history Patient has hyperlipidemia Patient has liver or kidney impaired function. Patient has any neoplasm Patient has psychiatric diseases. There is active infection in patient's body. Patient takes vitamin/mineral supplements. Patient takes medications like thyroid hormones, Anti hypertensives, contraceptives, diuretics and beta-blockers. Patient drinks alcohol or smokes. Patient has any allergy to sea buckthorn. Patient is pregnant or breastfeeds. Disease severity is above 5.5 based on DAS criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: before intervention and 30, 45, 90 days after intervention. Method of measurement: visual analog scale.;Number of tender joints. Timepoint: before intervention and 30, 45, 90 days after intervention. Method of measurement: Disease Activity Score Calculator for Rheumatoid Arthritis.;Number of swollen joints. Timepoint: before intervention and 30, 45, 90 days after intervention. Method of measurement: Disease Activity Score Calculator for Rheumatoid Arthritis.;ESR. Timepoint: Before intervention and 90 days after intervention. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Roshanak Salari
Mashhad University of Medical Sciences
Outcome results
None listed