Hypoxia due the mechanism of Covid-19. Covid 19
Conditions
Interventions
Intervention 1: Intervention group: The intervention group will receive standard treatment. In addition The intervention group will receive 400 mg oral pentoxifylline tablets made in Iran, Farabi Pha
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: confirmation of Covid-19 diagnosis by PCR test informed consent to participate in the study No history of allergy to methylxanthines Being hospitalized in the intensive care unit The patient should not be intubated arterial oxygen saturation less than 85% without oxygen therapy(room air or ambient air)
Exclusion criteria
Exclusion criteria: pregnancy and lactation Severe liver failure Severe renal failure Bleeding disorder and coagulopathy Hypersensitivity to the pentoxifylline(After prescribing)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Atrial of Oxygen saturation. Timepoint: Before the intervention and 48 hours,72 hours after the start of intervention. Method of measurement: Cardiac monitoring.;Measure of Arterial blood oxygen. Timepoint: Before the intervention and 48 hours,72 hours after the start of intervention. Method of measurement: ABG.;Blood pressure. Timepoint: Before the intervention and 48 hours,72 hours after the start of intervention. Method of measurement: Cardiac monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospitalization in Intensive care unit. Timepoint: Daily. Method of measurement: Check list. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarshid Abedi
Birjand University of Medical Sciences
Outcome results
None listed