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Evaluation of therapeutic effect of Simospan syrup on covid-19

Evaluation of therapeutic effect of Simospan syrup (contains of Thymus vulgaris, Hedera helix, Honey and Vitamin C) on duration of hospitalization in covid-19 patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210621051642N1
Enrollment
52
Registered
2021-07-05
Start date
2021-06-26
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

covid-19. COVID-19, virus identified

Interventions

Intervention 1: Control group: routine treatment based on physician's order. Intervention 2: Intervention group: routine treatment based on physician's order and simospan syrup (every 8 hours 6 cc fo

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age limitation (30-60 years old) Hospitalized patients with CT-scan findings in favor of Covid-19 disease Hospitalized patients with the amount of blood oxygen saturation below 93% Hospitalized patients with Chest X-ray findings in favor of pneumonia Hospitalized patients without underlying disease

Exclusion criteria

Exclusion criteria: Pregnancy and lactation End-stage Covid-19 patients Patients diagnosed with underlying disease and organ damage

Design outcomes

Primary

MeasureTime frame
The spent time to illness improvement. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Variable type is qualitative and its scale is nominal.the criterion of recovery records and descripts based on observations of data collecting man in checklist.relative criterion based on clinical symptoms:1-non-admission along with the return of normal activity-2-non-admission along without the return of normal activity-3-admission without the need for oxygentherapy-4-admission with the need for oxygentherapy-5-admission with the need to receive high speed oxygen from the nose or non invasive ventilation or both-6-admission with the need to receive oxygen therapy with invasive ventilation or oxygen therapy from non pulmonary pathways or both-7- patient's death.;Discharge from hospital. Timepoint: After the start of intervention. Method of measurement: Duration of hospitalization.

Secondary

MeasureTime frame
The blood level of ALT enzyme. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Spectrometer.;The blood level of BUN. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Spectrometer.;The blood level of creatinine. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Spectrometer.;The blood level of AST enzyme. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Spectrometer.;RBC count. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Cell counter.;WBC count. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Cell counter.;The blood level of HG. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Auto analyzer machine.;The blood level of HCT. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Auto analyzer machine.;CRP blood test. Timepoint: Before and 5 days after the start of intervention. Method of measurement: ELISA kits.;ESR test. Timepoint: Before and 5 days after the start of intervention. Method of measurement: Wintrobe method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSajad Seyedi

Sabzevar University of Medical Sciences

sajadseyedi2004@gmail.com+98 51 4401 1954

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026