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Antimicrobial efficacy of combination of chlorhexidine and nano-silver fluoride mouthwashes on orthodontic patients

The antimicrobial efficacy of combination of chlorhexidine and nano-silver fluoride mouthwashes on Streptococcus mutans in orthodontic patients (Randomized clinical trial)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210620051635N1
Enrollment
45
Registered
2021-07-30
Start date
2021-06-21
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental caries in orthodontic patients.

Interventions

The first group (n = 15): Chlorhexidine mouthwash 0.2% , The second group (n = 15): Silver fluoride mouthwash 0.04% ,The third group (n = 15): Mouthwash containing 0.1% chlorhexidine mixture and silve

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients not receiving antibiotic therapy for the past three weeks Patients not receiving fluoride therapy for the past three weeks patients agreed with the informed written consent previous to the study Patients in the 20-40 age range

Exclusion criteria

Exclusion criteria: Patients with dental prostheses (crown and bridge) Patients with soft tissue pathology Patients with poor oral health (DMFT> 8) Smokers Patients with orthodontic removable appliances

Design outcomes

Primary

MeasureTime frame
Time?The amount of bacteria?Studied groups. Timepoint: Before intervention - 14 days after the intervention (Using Mouthwash). Method of measurement: Time: 2 times (before and after using mouthwash (first day and 14th)) Bacterial content: Colony counting unit study groups: Chlorhexidine, silver fluoride, combination of Chlorhexidine and silver fluoride.

Secondary

MeasureTime frame
Time, The amount of bacteria, Study groups. Timepoint: 2 times (before intervention and 14 days after intervention). Method of measurement: Time: 2 times (before intervention _ 14 days after intervention) Bacterial content: colony-forming unit Study groups: 2 times (before intervention _14 days after intervention).

Countries

Iran (Islamic Republic of)

Contacts

Public Contactamir hooman sadr haghighi

Tabriz University of Medical Sciences

Hooman_sadr7@yahoo.com+98 41 3557 2636

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026