cardiac catheterization.
Conditions
Interventions
Intervention 1: Intervention group: from 2 hours before to 24 to 48 hours after the procedure, oral nicorandil 10 mg 3 times a day, and intravenous normal saline from 2 hours before to 6 hours after t
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Based on the risk score,Have a moderate risk or at least two risk factors for contrast nephropathy. EF less than 40 Diabetes mellitus. Blood pressure above 140/90 mm Hg, Renal failure (GFR) less than 60 No pregnancy (basal serum creatinine above 1.5 mg / dl) Minimum age 18
Exclusion criteria
Exclusion criteria: Pregnancy Pulmonary edema Cardiogenic shock Multiple myeloma Acute renal failure ESRD(GFR<15 mg/dl) Allergy to media contrast Nicorandil allergy Facing media contrast in the last 7 days NAC and metformin and dopamine and sodium bicarbonate and mannitol and phenol dopam in the last 48 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Laboratory banksHb, FBS, HCT, TG, LDL, HDL,ChoL. Timepoint: The first step at the beginning of the study. Method of measurement: Sampling. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum creatinine and creatinine clearance and BUN. Timepoint: It is measured 24 to 48 hours after the procedure. Method of measurement: Protocol based analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Abdollahimoghaddam
Mashhad University of Medical Sciences
Outcome results
None listed