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Evaluation of the effect of probiotic prophylaxis in children with nephrotic syndrome

Evaluation of the effectiveness of probiotic( lactobacillus reuteri )on the course of the disease and response to treatment of children with nephrotic syndrome.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210620051628N1
Enrollment
48
Registered
2021-07-13
Start date
2021-08-23
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nephrotic syndrome. Nephrotic syndrome

Interventions

Intervention 1: Intervention group:probiotic is administered orally from rotflore sachet (containing 10 to 8 rotary lactobacilli per sachet) daily. Intervention 2: Control group: In this group, patie

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 14 Years

Inclusion criteria

Inclusion criteria: All children 2 to 14 years old who are diagnosed with idiopathic nephrotic syndrome are referred to the pediatric nephrology clinic of Besat Hospital and their disease is approved by a pediatric nephrologist based on diagnostic criteria.

Exclusion criteria

Exclusion criteria: congenital nephrotic syndrome Secondary nephrotic syndrome Associated with glomerulonephritis (nephrotic nephrotic syndrome) Accompanied by kidney failure Accompanied by high blood pressure Start antibiotics for any reason Age less than 2 years and more than 14 years Dissatisfaction

Design outcomes

Primary

MeasureTime frame
Follow-up of relapse and treatment of patients. Timepoint: MONTHLY. Method of measurement: Presence or absence of proteinuria.

Secondary

MeasureTime frame
Recurrence of nephrotic syndrome in treated patients. Timepoint: En MONTHLY. Method of measurement: Presence of protein in urine.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholamreza Kalvandi

Hamedan University of Medical Sciences

g.kalvandi@umsha.ac.ir+98 81 3838 0426

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026