Parkinson's disease. Parkinson's disease
Conditions
Interventions
Intervention 1: Intervention group: The duration of the intervention is 12 weeks. The nicotine-rich group will receive 20 micrograms of nicotine per day through diet. Intervention 2: Control group:The
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Parkinson's patients who have been diagnosed with Parkinson's disease according to the MDS clinical diagnostic criteria for Parkinson's disease Age over 50 years old Patients receiving dopaminergic therapy who have reached a stable dose to control symptoms Patients who have signed the consent form
Exclusion criteria
Exclusion criteria: Severe systemic or psychological disease History of gastrointestinal bleeding Taking aspirin with a dose of more than 325 mg per day Taking drugs that increase insulin sensitivity, heparin, warfarin or other anticoagulants and antiplatelets Exposure to cigarette smoke Alcohol consumption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of disease severity from the Unified Parkinson's Disease Rating Scale (UPDRS). Timepoint: At the beginning and end of the study. Method of measurement: Evaluation of disease severity from the Unified Parkinson's Disease Rating Scale (UPDRS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDoctor Mohammadhasan Javanbakht
Tehran University of Medical Sciences
Outcome results
None listed