Depression Disorder. Major depressive disorder, single episode, moderate
Conditions
Interventions
Intervention 1: Intervention group 1: continuous aerobic exercise for 8 weeks and 3 sessions per week. In the first week, the duration of training will be 20 minutes and the intensity will be 50% of h
Sponsors
Razi University
Eligibility
Sex/Gender
Male
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Not participation in regular exercise training over the last 6 months Having moderate depression confirmed by a specialist Getting the certification of no prohibition of participating in exercise training program from a specialist
Exclusion criteria
Exclusion criteria: Any other psychiatric disorder other than depression Alcohol or substance addiction Inability to perform exercise interventions Cardiovascular and pulmonary diseases Obesity (body mass index more than 30) Refusal to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in serum levels of brain-derived neurotrophic factor. Timepoint: Before starting the intervention, and 8 weeks after starting the intervention. Method of measurement: By the use of blood sample and ELISA method.;Change in quality of life. Timepoint: Before starting the intervention, and 8 weeks after starting the intervention. Method of measurement: World health organization standard quality of life questionnaire (short version).;Change in depression severity. Timepoint: Before starting the intervention, and 8 weeks after starting the intervention. Method of measurement: Hamilton Depression Rating Scale.;Change in cognitive flexibility. Timepoint: Before starting the intervention, and 8 weeks after starting the intervention. Method of measurement: The 20-item cognitive flexibility inventory (Dennis and Vander Wal). | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in physical self-concept. Timepoint: Before intervention and after 8 weeks of intervention. Method of measurement: Physical self-concept questionnaire.;Change in the quality of sleep. Timepoint: Before intervention and after 8 weeks of intervention. Method of measurement: Pittsburgh Sleep Quality Index.;Change in anxiety. Timepoint: Before intervention and after 8 weeks of intervention. Method of measurement: Beck Anxiety Inventory.;Change in self-esteem. Timepoint: Before intervention and after 8 weeks of intervention. Method of measurement: Rosenberg’s Self-Esteem Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEhsan Amiri
Razi University
Outcome results
None listed