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Thalidomide and moderate COVID-19 pneumonia

Effect of Thalidomide on moderate COVID-19 pneumonia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210614051574N5
Enrollment
100
Registered
2021-09-13
Start date
2021-09-22
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. COVID-19, virus identified

Interventions

Intervention 1: Intervention group: Patients in this group will receive 100 mg thalidomide tablets made by Kobel Daru Company orally for 14 days along with other routine treatments for pneumonia cause

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Definitive laboratory results for Covid-19 Radiographic results of lung injury and infection Less than 5 days have passed since the confirmation of the infection Moderate disease severity based on the World Health Organization classification criteria

Exclusion criteria

Exclusion criteria: Pregnancy Breastfeeding Receive thalidomide or other experimental drugs related to the treatment of Covid-19 within one month prior to enrollment Existence of a history of thromboembolism unrelated to recent Covid-19 disease History of interstitial lung disease

Design outcomes

Primary

MeasureTime frame
Complete clinical recovery time. Timepoint: After interventions. Method of measurement: Examination and clinical signs.;Mortality rate. Timepoint: After interventions. Method of measurement: Patients' records.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGhasem Mohammadsharifi

Esfahan University of Medical Sciences

mohammadsharifi.ghasem@gmail.com+98 31 3729 4005

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026