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Investigating the effect of emulsion containing olive oil and calcium in reducing radiation dermatitis caused by radiotherapy in breast cancer patients

The effect of olive oil and calcium hydroxide emulsion on radiation radiation-induced dermatitis in breast cancer patients referred to Adjuvant RadiationTherapy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210614051571N1
Enrollment
120
Registered
2023-06-07
Start date
2021-07-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer. Malignant neoplasm of breast

Interventions

Intervention 1: Control group: routine radiotherapy treatment + castor oil, which is sprayed on the target area half an hour before radiotherapy, like other groups. Intervention 2: Intervention group:

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 20 to 80 years who have undergone breast tumor surgery and are indicated for adjuvant radiotherapy (both MRM and BCS) Its pathology type is invasive breastbe carcinoma Patients with a mass larger than 5 cm and at least one lymph node involved and lampooning Menopausal premenopause and postmenopausal age Do not use any other topical medication during treatment

Exclusion criteria

Exclusion criteria: Diabetic patients Those with inflammatory breast carcinoma. People with known allergies to olive oil and calcium hydroxide. People with scleroderma or lung parenchymal disease.

Design outcomes

Primary

MeasureTime frame
Radiation-induced dermatitis (erythema, dry desquamative, wet desquamative, necrosis). Timepoint: At the beginning of the study and then at the end of the first, second, third and fourth week. Method of measurement: RTOG questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReyhaneh Habibiyan

Shahre-kord University of Medical Sciences

St-habibiyan.r@skums.ac.ir+98 38 3222 0016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026