Cell therapy in hypopigmented patches following burn scar

Phase I/II clinical trial of melanocyte and keratinocyte transplantation in hypopigmented burn scar patches

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210612051545N1

Enrollment

Registered

2021-06-16

Start date

2021-06-22

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn scar. Calcification and ossification of muscles associated with burns

Interventions

Intervention group: Autologous keratinocyte and melanocyte suspension, single dose, 10-15 x10(6) cells, transplantation following laser, Motahari hospital clean room.

Eligibility

Sex/Gender

All

Age

12 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age 12 to 65 years Acute burn for more than 6 months ago

Exclusion criteria

Exclusion criteria: pregnancy or lactating Infection in donor or reciept site History of malignancy Immuno-suppressive drugs in past 3 months

Design outcomes

Primary

Measure	Time frame
Safety of intervention method. Timepoint: 1, 3, and 6 months after transplantation. Method of measurement: medical history and physical exam.	—

Secondary

Measure	Time frame
Repigmentation rate. Timepoint: 1, 3, and 6 months after transplantation. Method of measurement: Image J software.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoheila Naderi

Iran University of Medical Sciences

soheila_naderi2@yahoo.com+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026