Investigating the effect of hyaluronic acid hydrogel loaded with terbinafine lipid nanostructures in the treatment of patients with onychomycosis

Formulation design and evaluation of the effect of hyaluronic acid hydrogel loaded with terbinafine lipid nanostructures in the treatment of patients with onychomycosis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210611051539N4

Enrollment

Registered

2023-11-19

Start date

2023-11-06

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Onychomycosis. Tinea unguium

Interventions

Intervention 1: Intervention group: For patients with onychomycosis, terbinafine hydrogel and placebo in Mazandaran University of Medical Sciences in 100 gram tubes, 2 times a day for 1 months. This

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients with onychomycosis

Exclusion criteria

Exclusion criteria: Taking antifungal drugs Conscious withdrawal of the patient Leaving the plan with the order of a dermatologist

Design outcomes

Primary

Measure	Time frame
Improvment of fungal lesions in term of clinical and mycological criteria. Timepoint: before the start of the intervention and 1, 2 and 4 weeks after the start of the treatment. Method of measurement: Examination of clinical symptoms in terms of lesion healing by a doctor and examination in terms of direct smear and fungal culture in the interval of 1, 2 and 4 weeks.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam Moazeni

Mazandaran University of Medical Sciences

moazeni.maryam@gmail.com+98 11 3325 7911

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026