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treatment schizophrenia patients: double-blind randomized controlled trial

Title: The Effectiveness of tDCS over the DLPFC on reducing clinical symptomsimproving working memory and aberrant EEG functional connectivity in resting state schizophrenia patients: double-blind randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210608051514N1
Enrollment
30
Registered
2021-06-20
Start date
2021-07-23
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia. Schizophrenia

Interventions

Intervention 1: Intervention group: Treatment with stimulation of extracranial direct current with a current of 2 mA for 20 minutes on the lateral dorsal forehead cortex will receive ten sessions for

Sponsors

Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Having a diagnosis of schizophrenia Having the ability to write informed consent Experience positive symptoms despite a month of stabilization in medication dose The same dose and medicine Being a man Being right-handed Age 65_18 years The dose of antipsychotic medication used by the person is constant at the beginning and during the research Stabilization in drug treatment for at least 6 weeks

Exclusion criteria

Exclusion criteria: Have a history of suicide and abuse of alcohol and substances other than caffeine and tobacco in the past month Have a history of neurological diseases such as Parkinson's, epilepsy, seizures, stroke and cardiovascular problems Having diseases related to the scalp Having a history of head trauma and the presence of a device or tool in the head Withdrawal from the study after absence in two consecutive sessions of treatment.

Design outcomes

Primary

MeasureTime frame
Negative symptoms:Theoretical definition: It is one of the clinical symptoms in schizophrenia that includes superficial emotion, poor speech, lack of motivation, unhappiness and social transgression.Operational definition: The score that a person gets from the positive and negative symptoms of schizophrenia.Positive symptoms: Theoretical definition includes delusions, delusions, disturbed speech, and disturbed behavior that persist throughout a one-month period.Operational definition: The score that a person gets from the positive and negative symptoms of schizophrenia. Timepoint: Pre-test-post-test-one-month follow-up-quarterly follow-up. Method of measurement: The score that a person gets from the questionnaire for measuring positive and negative symptoms in schizophrenia.

Secondary

MeasureTime frame
Working memory:Theoretical definition: means the ability to store and manipulate information in memory, which is an essential prerequisite for complex cognitive tasks such as learning, reasoning and comprehension. Timepoint: Pre-test-post-test-one-month follow-up-quarterly follow-up. Method of measurement: The score a person gets from the n back test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohsen Dadashi

Zanjan University of Medical Sciences

mohsen.dadashi@gmail.com+98 21 8670 5504

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026