The effect of hypertension due to cholecystectomy surgery on postoperative pain

The effect of pneumoperitoneum-induced hypertension during laparoscopic cholecystectomy under general anesthesia on postoperative pain compared with normal blood pressure induced by intravenous nitroglycerin

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210607051501N1

Enrollment

Registered

2021-10-24

Start date

2021-07-23

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystitis.

Interventions

Intervention 1: Intervention group: The intervention group includes patients who meet the inclusion criteria and undergo laparoscopic cholecystectomy. The intervention is surgery-induced pneumoperiton

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: No underlying disorders (ASA 1) Aged between 20 to 60 yr

Exclusion criteria

Exclusion criteria: Having analgesic agent during last week

Design outcomes

Primary

Measure	Time frame
Postoperative pain score. Timepoint: The postoperative pain intensity (VAS) will record in hours 2, 8, 12 and 24 after surgery. Method of measurement: Visual Analogue Scale.;Pethedine dosage after surgery. Timepoint: The total dose of pethedine used for pain control will record in hours 2, 8, 12 and 24 after surgery. Method of measurement: Data record forms.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Khatibi

Iran University of Medical Sciences

khatibi.al@iums.ac.ir+98 21 8214 1600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026