Effect of herbal toothpaste containing Salvadora persica, Prpolis and Stevia rebaudiana on group of Streptococcus mutans bacteria

Investigation of herbal toothpaste containing Salvadora persica, Prpolis and Stevia rebaudiana on group of Streptococcus mutans bacteria and its comparison whith a common chemichal toothpaste.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210604051492N1

Enrollment

Registered

2021-07-08

Start date

2021-05-31

Completion date

Unknown

Last updated

2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The amount of bacteria in the group of Streptococcus mutans saliva.

Interventions

Intervention 1: Intervention group: Herbal toothpaste, twice a day for 14 days , Albodent herbal toothpaste factory of Armaghan Salamat Alvand Faraz Company. Intervention 2: Intervention group: Chemic

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Have normal periodontium Have no systemic illness or history of antibiotics, anti-inflammatory drugs and periodontal treatment in the past 3 months Have at least 20 teeth People who are definitely allergic to the herbal ingredients in toothpaste.

Exclusion criteria

Exclusion criteria: Smoker people Pregnant people Brestfeeding people People have fixed or removable orthodontics and dental Prosthesis applience

Design outcomes

Primary

Measure	Time frame
The amount of bacteria in the group of Streptococcus mutans saliva. Timepoint: At the beginning of the study and day 14 after consuming toothpaste. Method of measurement: The number of colonies formed in each plate is calculated by CFU method.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Amin Motevallia

Ghoum University of Medical Sciences

aminmotevallia@gmail.com+98 25 9770 0094

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026