Retained products of conception following (spontaneous) AND Retained products of conception following failed attempted abortion. Incomplete spontaneous abortion without complication
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: The letrozole group includes women (under 20 weeks) who have residual pregnancy greater than 2 cm according to ultrasound after miscarriage (spo
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: a) Women who have a spontaneous abortion Women who are candidates for abortion for medical reasons or according to the opinion of a legal physician. Age between 18 and 45 years There is remnants of pregnancy on ultrasound (more than 2 cm) No serious medical problems or chronic diseases (heart, liver, kidney diseases, or uncontrolled diabetes) No allergy to letrozole No allergy to misoprostol Informed consent
Exclusion criteria
Exclusion criteria: Severe side effects (severe bleeding, allergic reactions, severe abdominal pain, etc.) Failure to respond to treatment within 3 weeks Need for alternative therapeutic interventions (such as misoprostol or surgical curettage) New or diagnosed serious diseases (such as acute infections, heart problems, or autoimmune diseases) Patient unwillingness to continue treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete evacuation of the products of pregnancy. Timepoint: 3 weeks after starting treatment. Method of measurement: Examination of the expulsion of the products of pregnancy through transvaginal ultrasound.;Amount and type of bleeding. Timepoint: Ultrasound of the patient three weeks later. Method of measurement: Recording clinical symptoms and patient observations (bleeding intensity as mild, moderate, or severe and presence of clot). | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects and possible complications. Timepoint: 3 weeks after starting treatment. Method of measurement: Recording and evaluating side effects such as abdominal pain, nausea, headache, or allergic reactions, the presence of residues less than two centimeters is considered a success of the treatment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Roya Kabodmehri
Rasht University of Medical Sciences
Outcome results
None listed