Female infertility. Female infertility, unspecified
Conditions
Interventions
Intervention 1: Intervention group: All patients will be given a low dose OCP (ethinyl estradiol 30 µg + levonorgestrel 150 µg) from day 3 to 21 of the menstrual cycle. On day 21 of the menstrual cycl
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
No minimum to 40 Years
Inclusion criteria
Inclusion criteria: Women with full consent to participate in the study Women under the age of 40 FSH levels less than 10
Exclusion criteria
Exclusion criteria: Absence of PCOS Absence of azoospermia Absence of moderate to severe endometriosis Insensitivity to GnRh
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of biochemical and clinical pregnancies. Timepoint: Biochemical pregnancies will be evaluated based on a positive ßhCG pregnancy test, and clinical pregnancies will be evaluated based on observation of the pregnancy sac and fetus at week seven of pregnancy. Method of measurement: 14 days after embryo transfer, biochemical pregnancy is confirmed by a positive ßhCG serum test, and clinical pregnancy is confirmed by vaginal ultrasound at 7 weeks of gestation.;Estradiol levels. Timepoint: On the day of hCG administration. Method of measurement: Evaluation of serum estradiol levels.;Progesterone levels. Timepoint: On the day of hCG administration. Method of measurement: Evaluation of serum Progesterone levels.;Duration of ovarian stimulation. Timepoint: From the second day until the time of HCG injection. Method of measurement: Number of days.;Dose of gonadotropin consumption. Timepoint: From the second day until the time of HCG injection. Method of measurement: Based on the dose of ampoules required for ovarian stimulation (75, 450 and 900 IU).;Fertilization. Timepoint: 12-18 hours after Pick up. Method of measurement: Based on 2PN observations by the embryologist.;Implantation. Timepoint: At 7 weeks. Method of measurement: The gestational sac seen on ultrasound by gynecologist.;Total number of oocytes obtained. Timepoint: On the day of ovarian puncture. Method of measurement: Based on the number of oocytes obtained.;The total number of metaphase II stage oocytes. Timepoint: On the day of oocyte pickup operation. Method of measurement: Based on the evaluation of oocyte characteristics by the embryologist.;Ovarian hyperstimulation syndrome. Timepoint: 3-14 days after pickup operation. Method of measurement: Based on the observation of sonographic and clinical signs of OHSS after pickup operation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dosage of gonadotropins. Timepoint: From day 2 until the time of HcG injection. Method of measurement: Number of HMG ampoules.;Duration of ovarian stimulation. Timepoint: From day 2 until the time of HcG injection. Method of measurement: Count the number of days.;Fertilization. Timepoint: 12-18 hours after pickup. Method of measurement: View 2 PN by embryologist.;Implantation. Timepoint: At 7 weeks. Method of measurement: By observing the pregnancy sac on ultrasound by a gynecologist.;Total number of oocytes. Timepoint: On the day of oocyte pickup operation. Method of measurement: Oocyte count.;The total number of oocytes metaphase II stage. Timepoint: On the day of operation Oocyte pickup (OPU). Method of measurement: Based on the evaluation of oocyte characteristics by the embryologist.;Ovarian hyperstimulation syndrome. Timepoint: 3-14 days after pickup operation. Method of measurement: Based on the observation of sonographic and clinical signs of OHSS.;Estradiol levels. Timepoint: On the day of hCG administration. Method of measurement: Based on serum Estradiol level at hCG administration (in picograms per ml).;Progesterone levels. Timepoint: On the day of hCG administration. Method of measurement: Based on serum Estradiol level at hCG administration (In nanograms per milliliter). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Roya Kabodmehri
Rasht University of Medical Sciences
Outcome results
None listed