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Evaluation of clinical trial of self-assembling peptide nanofiber in sinus cavity repair

Evaluation of clinical trial of self-assembling peptide nanofiber in sinus cavity repair

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210526051407N1
Enrollment
18
Registered
2021-06-27
Start date
2021-07-06
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone resorption in the maxilla.

Interventions

Intervention 1: Second Intervention group: Self-assembling peptide nanofiber (the company-made) is placed in a single dose (1 ml) to repair the sinus cavity and is tested for 6 months. Intervention 2:

Sponsors

Iran University of Medical Sciences
Lead Sponsor
Knowledge enterprise company “Tavakol Pars Biomimetic Technologies Company
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patient will require sinus augmentation bone height between alveolar crest and maxillary sinus less than 8 millimetres. Patient has good oral and dental hygiene Do not have maxillary sinus diseases

Exclusion criteria

Exclusion criteria: Smoking Pregnancy and lactation Uncontrolled diabetes Alcohol consumption Autoimmune diseases Cancer and undergoing chemotherapy

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: The fourteenth day. Method of measurement: McGill Pain Questionnaire (MPQ).;Wound healing. Timepoint: The fourteenth day. Method of measurement: Using dental tweezers by examining alveolar osteitis based on BLUM'S criteria.;The amount of vertical height. Timepoint: Baseline and after 6 months. Method of measurement: CBCT.;Implant stability. Timepoint: After 6 months. Method of measurement: OSTELL.;Bone tissue quality. Timepoint: Post-implantation. Method of measurement: Tissue staining.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShima Tavakol

Iran University of Medical Sciences

shima.tavakol@yahoo.com+98 21 8862 2578

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026