The effect of combined exercise and detraining on overweight and obese girls with precocious puberty

The effect of 12 weeks of combined exercise and detraining on levels of adipokines, cytokines, puberty symptoms and mental health in overweight and obese girls with central precocious puberty

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210525051396N1

Enrollment

Registered

2021-11-12

Start date

2019-05-22

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

central precocious puberty.

Interventions

Intervention 1: Intervention group:. Intervention 2: Control group:.

Eligibility

Sex/Gender

Female

Age

7 Years to 9 Years

Inclusion criteria

Inclusion criteria: Girls with central precocious puberty Having a BMI higher than 19 The age range of 7 to 9 years One year has passed since they were diagnosed with precocious puberty Being on medication for one year Being treated with Differlin drug Taking medication 1 ml every 28 days

Exclusion criteria

Exclusion criteria: having another illness taking another medicine having a special diet being active in another sport being connected to drugs

Design outcomes

Primary

Measure	Time frame
Cytokines. Timepoint: Baseline, 12 weeks, 16 weeks. Method of measurement: Blood sampling and use of laboratory kits.;Stimulating hormones Sex hormones (lutein and follicle stimulating). Timepoint: Baseline, 12 weeks, 16 weeks. Method of measurement: Blood sampling and use of laboratory kits.;Signs of puberty (uterine and ovarian size, bone age). Timepoint: Baseline, 12 weeks, 16 weeks. Method of measurement: Ultrasound and Grolich and Pyle Atlas.	—

Measure

Time frame

Cytokines. Timepoint: Baseline, 12 weeks, 16 weeks. Method of measurement: Blood sampling and use of laboratory kits.;Stimulating hormones Sex hormones (lutein and follicle stimulating). Timepoint: Baseline, 12 weeks, 16 weeks. Method of measurement: Blood sampling and use of laboratory kits.;Signs of puberty (uterine and ovarian size, bone age). Timepoint: Baseline, 12 weeks, 16 weeks. Method of measurement: Ultrasound and Grolich and Pyle Atlas.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactElnaz Shokri

Bu-Ali Sina university

e.shokri7@gmail.com+98 81 3420 0234

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026