Burn. Burn and corrosion of head, face, and neck
Conditions
Interventions
Intervention 1: Intervention group (Patients receiving RIPC procedure): RIPC procedure will be performed on the first day of hospitalization under the following protocol twice with an interval of 12 h
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age between 18 to 65 years Acute burn injury within 24 hours 20 to 50 percent TBSA (total body surface area) Patient classified as class 1 ASA (American Society of Anesthesiologists) : Normal healthy person Signed informed consent
Exclusion criteria
Exclusion criteria: Severe hypertension = BP (Blood pressure) =160/90 mmHg Ischemic changes in ECG (Electrocardiogram) Pregnant women Peripheral vascular diseases Inhalation injury Burn shock: decreased CO (Cardiac output), increased systemic vascular resistance, hypovolemia and hypoperfusion induced by severe burn injury Patients with burn injury in both upper limbs in which the procedure couldn't be performed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Graft to TBSA (total body surface area) percent ratio. Timepoint: At the admission. Method of measurement: Measurements based on Wallace criteria.;Total fluid requirement. Timepoint: At discharge. Method of measurement: Based on patients' files.;Hospital stay. Timepoint: At discharge. Method of measurement: Based on patients' files.;Final clinical outcome. Timepoint: At discharge. Method of measurement: Based on patients' files. | — |
Secondary
| Measure | Time frame |
|---|---|
| Infection. Timepoint: Day 1, 3, 7, 14 and 28 post admission. Method of measurement: Based on examination done by evaluators.;Itching. Timepoint: Day 1, 3, 7, 14 and 28 post admission. Method of measurement: Asking patients.;Burning. Timepoint: Day 1, 3, 7, 14 and 28 post admission. Method of measurement: Asking patients.;Shock index. Timepoint: Hour 1, 6, 12, 24 post admission. Method of measurement: Heartbeat per minute / systolic Blood pressure in mmHg.;SIRS (Systemic inflammatory response syndrome). Timepoint: Day 1, 3, 7, 14 and 28 ?post admission. Method of measurement: Based on body temperature, heart rate, respiratory rate, and WBC (white blood cells) count.;Cr (creatinine). Timepoint: Day 1, 3, 7, 14 and 28 ?post admission. Method of measurement: Based on patients' laboratory results. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Reza Mobayen
Rasht University of Medical Sciences
Outcome results
None listed