Oxandrolone and propranolole in burn patients

Assessing the effects of Oxandrolone and Propranolole administration on improving post-burn hyper-metabolic changes

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210524051384N4

Enrollment

768

Registered

2021-10-18

Start date

2021-10-23

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Burn Injury. Condition 2: Burn Injury. Contact with hot drinks, food, fats and cooking oils ???? ????? ?? ???? ???? ??? ? ????

Interventions

Intervention 1: Intervention group: At the beginning of the study, burn patients referred to the Burn and Regenerative research center of Velayat, according to age, are divided into 3 groups: children

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Sever burn injury ( TBSA>20%) aging 0 to 80 years Negative Pregnancy test in female patients of child bearing age Informed consent of patients entering the study

Exclusion criteria

Exclusion criteria: Not treated Malignancies, known history of AIDS and complex related diseases to AIDS and HIV. History of recent MI (Less than 6 weeks ago) Tuberose Sclerosis, Arthritis, Cirrhosis, Hyperlipidemia, Bone or Endocrine disorders, Autoimmune Diseases Long term consumption of corticosteroids or NSAIDS Diabetic Mellitus Prior to burn injury Renal failure ( Creatinine level more than 3) Hepatic Disease ( Bilirubin level more than 3) Anoxic Brain injury patients suffering from asthma and history of airway constriction

Design outcomes

Primary

Measure	Time frame
Metabolic State of Burn Patient. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: Mercury sphygmomanometer, Caliper, Ruler, Scales, Laboratory tests.	—

Secondary

Measure	Time frame
Weight. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: with scale , on kilogram.;BMI Changes. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: Based on weight and height.;Wrist to hip ratio. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: using a centimeter stick.;Triceps Skinfold Thickness. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: Using a Caliper.;Hepatic transaminase. Timepoint: In children group: on admission, on discharge, and 1, 3, 6 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: Blood test.	—

Measure

Time frame

Weight. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: with scale , on kilogram.;BMI Changes. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: Based on weight and height.;Wrist to hip ratio. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: using a centimeter stick.;Triceps Skinfold Thickness. Timepoint: In children group: on admission, on discharge, and 1, 2, 4. 6. 9 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: Using a Caliper.;Hepatic transaminase. Timepoint: In children group: on admission, on discharge, and 1, 3, 6 and 12 months after discharge. In adults group: on admission, on discharge and 40 days after discharge. In elderly Group: On admission and on discharge. Method of measurement: Blood test.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Haghani

Rasht University of Medical Sciences

r.haghani.r@gmail.com+98 13 3336 8540

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026