Burns. Burns of multiple regions, at least one burn of third degree mentioned, Burns of multiple regions, no more than second-degree burns mentioned
Conditions
Interventions
Intervention 1: Intervention group: The probiotic product is two Lactocare capsules daily for intervention group (A). Two oral capsules will be started daily for ten days after the burn and continue
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 89 Years
Inclusion criteria
Inclusion criteria: Patients 15-89 years aged, within 24 hours after the occurrence of second or third degree burns with TBSA (Total Body Surface Area) between 20-70%, People with thermal burns are not accompanied by other trauma and have the ability to feed by the digestive system
Exclusion criteria
Exclusion criteria: Patients with digestive diseases Immunodeficiency diseases Chronic diseases such as diabetes and sepsis during hospitalization pregnancy and breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Body Surface Area. Timepoint: Percentage of burns. Method of measurement: Measurements based on Wallace criteria.;Proportion of length of hospital stay to TBSA. Timepoint: Lenght of hospitalization based on patient records and follow-up until the day of discharge to TBSA. Method of measurement: Number.;Mortality. Timepoint: Death means the absence of vital signs during the patient's hospitalization. Method of measurement: Dead / Alive.;Number of days of antibiotic usage. Timepoint: Lenght of hospitalization based on patient records and follow-up until the day of discharge. Method of measurement: Based on day.;Number of days of taking antifungal medicine. Timepoint: Based on the patient's record and follow-up until the day of discharge. Method of measurement: Based on day.;Number of days of gastric complications (diarrhea, constipation, vomiting, laxative used). Timepoint: Based on the patient's history and check-up and follow-up until the day of discharge. Method of measurement: Based on day.;Study group. Timepoint: Based on random assignment to study groups. Method of measurement: Intervention / Control. | — |
Secondary
| Measure | Time frame |
|---|---|
| Graft loss. Timepoint: Graft loss that is diagnosed under the supervision of a surgeon and due to symptoms such as swelling, redness, infection, etc. Method of measurement: Yes / no.;WLOS / TBSA (wound healing duration ratio to TBSA). Timepoint: Based on the expert's observations about the location of the skin wound. Method of measurement: Number.;Number of days of infection. Timepoint: Based on evidence and results of blood or urine culture or wound or sputum. Method of measurement: Day.;CRP serum levels. Timepoint: Based on laboratory results. Day of hospitalization and the fourth, seventh, fourteenth days of hospitalization. Method of measurement: mg/L.;IgA serum levels. Timepoint: Based on laboratory results. Day of hospitalization and the fourth, seventh, fourteenth days of hospitalization. Method of measurement: mg/dL.;Blood lymphocyte and neutrophil count. Timepoint: Based on laboratory results. Day of hospitalization and the fourth, seventh, fourteenth days of hospitalization. Method of measurement: cells/mm?.;Albumin serum levels. Timepoint: Based on laboratory results. Day of hospitalization and the fourth, seventh, fourteenth days of hospitalization. Method of measurement: gr/dL. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Mohammadreza Mobayen
Rasht University of Medical Sciences
Outcome results
None listed