covid19. COVID19, virus identified
Conditions
Interventions
Intervention 1: Intervention group 1: Nasal spray Desferal + Zinc,chemical ingredients: desferrioxamine (500mg) plus Zinc acetate (200 mg) in a volume of 10 cc.Dosing: 2 Puffs in the nose every eight
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Informed and written consent of patient with Coronavirus Confirmation disease by clinical and laboratory signs Serum creatinine less than two Milligram per Deciliter Absence of heart problems( myocarditis- heart failure ) Hemoglobin above 8 Gram per Deciliter Patients admitted to the ward with moderate symptoms 18 to 65 years
Exclusion criteria
Exclusion criteria: Ferritin lower than 100 milligram per deciliter Diabetes History of blood coagulation problems Pregnancy and Breastfeeding History of neurologic problems History of vision and hearing problems concomitant use of vitamin C Intubated patient History of Desferal or Zinc allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interleukin6. Timepoint: Before and after the intervention. Method of measurement: ELISA KIT.;Body temperature. Timepoint: Before the intervention and every day during the study. Method of measurement: Thermometer.;Oxygen saturation. Timepoint: Before the intervention and every day during the study. Method of measurement: Pulse oximeter.;Cough. Timepoint: Before the intervention and every day during the study. Method of measurement: questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospitalization. Timepoint: Admission period until hospital discharge. Method of measurement: Patient file.;Incidence of serious adverse events. Timepoint: Before intervention and daily during the study. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNavid Esmaeilzadeh Shahri
Shiraz University of Medical Sciences
Outcome results
None listed