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A comparison between the Effectiveness of two different oral pastes, Containing Triamcinolone and Licorice, on minor Aphthous lesions: A triple blind randomized clinical trial

A comparison between the Effectiveness of two different Oral pastes, containing Triamcinolone and Licorice, on Minor Aphthous lesions: A triple blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210519051341N1
Enrollment
60
Registered
2021-09-23
Start date
2021-08-30
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent oral Aphthae. Recurrent oral Aphthae

Interventions

Intervention 1: Intervention group: Patients in the intervention group receive a drug containing the Licorice active ingredient. They are trained to apply the gel on the Aphthous lesion 3 times a day

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with Minor Aphthous ulcers who have been visited within the first 24 hours of incidence of the lesion. Patients do not have any systemic diseases ( Hypertension, Diabetes, Hyperlipidemia, Behcet disease, Rheumatism disease) Don't use medicine, cigarettes, alcohol and addiction

Exclusion criteria

Exclusion criteria: An oral ulcer that is not an Aphthous lesion More than 48hrs passed from incidence of the lesion Allergic to herbal medicines Use of medicine, cigarettes, alcohol and addiction Systemic diseases

Design outcomes

Primary

MeasureTime frame
Amount of pain. Timepoint: Before taking oral paste and the third, fifth and seventh days of treatment. Method of measurement: On the visit days, we ask the patient to mark the amount of pain on the Visual Analogue Scale.;Healing duration. Timepoint: Before taking oral paste and the third, fifth and seventh days of treatment. Method of measurement: Days spent until complete healing of the lesion.;Size of the lesion. Timepoint: Before taking oral paste and the third, fifth and seventh days of treatment. Method of measurement: The largest diameter of the lesion is measured with the dental probe in millimetres.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdie Zarabadipour

Qazvin University of Medical Sciences

mzarabadipour@qums.ac.ir+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026