Major Depression. Major depressive disorder, single episode, unspecified
Conditions
Interventions
Intervention 1: Intervention group 1: Traditional transcranial stimulation, in the treatment of direct current stimulation from the skull, two electrodes, one positive pole and the other negative pole
Sponsors
Zanjan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Having diagnostic criteria for unipolar MDD based on psychiatrist diagnosis and clinical interview Age range between 75-18 years Failure to treat with at least one antidepressant Do not take antidepressants now or have a consistent medication regimen for the past 4 weeks Score 17 on the Hamilton Depression Inventory Willingness to participate in research Conscious consent to participate in research Have the opportunity to participate in evaluation and treatment sessions (daily) (in terms of distance, cost, etc.)
Exclusion criteria
Exclusion criteria: Diagnosis of bipolar disorder Diagnosis of substance use or alcohol Detection of dementia Diagnosis of personality disorder Diagnosis of brain injury, stroke or brain tumor Existence or history of psychosis Diagnosis of epilepsy or history of loss of consciousness Pregnancy Contraindications to the use of tDCS (cranial plates), such as those using a pacemaker. Currently or in the last 4 weeks the person has received another treatment for MDD (medication or other psychological treatments) Having diseases related to the scalp Having a history of head trauma and the presence of a device or tools in the head
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of people whose Beck questionnaire score is above 20. Timepoint: Measurement of depression before the intervention, in the tenth session of the intervention, after the intervention, one-month follow-up and three months after the intervention. Method of measurement: Beck Questionnaire.;Percentage of people whose Hamilton questionnaire score is above 17. Timepoint: Measurement before intervention, after the intervention, one-month follow-up and three months after the intervention. Method of measurement: Hamilton Depression Test.;Depression Score on the Montgomery–Åsberg Depression Rating Scale. Timepoint: Measurements before the intervention, after the intervention.one-month follow-up and three months after the intervention. Method of measurement: Montgomery–Åsberg Depression Rating Scale.;Cognitive test score in cantab test. Timepoint: Measurements before the intervention, after the intervention.one-month follow-up and three months after the intervention. Method of measurement: cantab test.;Analyze the electroencephalography results. Timepoint: Measurements before the intervention, after the intervention. Method of measurement: Electroencephalography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarzieh Abdi
Zanjan University of Medical Sciences
Outcome results
None listed