Effect of Quercetin on PCOS patients

Effect of quercetin on the inflammatory factors NfKb, TnfAlpha, Il6 and expression of the Nrf2 and Keap1 genes in poly cystic ovary syndrome (PCOS Patients)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210516051323N1

Enrollment

Registered

2021-11-16

Start date

2021-10-22

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poly Cystic Ovary Syndrome.

Interventions

Intervention 1: For Intervention Group: quercetin, Orally 500 mg/day (1 Cap.) for 40 days from the beginning of the menstruation cycle till oocyte retrieval. Intervention 2: Intervention group: Placeb

Eligibility

Sex/Gender

Female

Age

20 Years to 37 Years

Inclusion criteria

Inclusion criteria: Infertility with documented PCOS & Hyperandrogenism;20-37Y/O; Candidate for IVF Cycle; If have male factor; it must mild to moderate form, not non-obstructive azospermia; If have other female factor; only cervical & tubal factors are acceptable.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Inflamatory factors TNfAlpha, IL6. Timepoint: Before consumption and after puncture surgery. Method of measurement: Elaysa Test on blood sample.	—

Secondary

Measure	Time frame
Effects on expression of Nrf2-Keap1 genes. Timepoint: After puncture surgery. Method of measurement: Real Time PCR Device records.;Protein expression, Keap-1. Timepoint: After the intervention. Method of measurement: western blot.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSima Vaez

Islamic Azad University

vaezmrs@gmail.com+98 21 4022 8954

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026