The effect of valerian and lavender essential oil on coronary heart disease

Evaluation of the effect of aromatherapy with valerian and lavender essential oil on vital signs, drug use and headache relief due to nitroglycerin infusion in coronary artery disease

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210516051316N1

Enrollment

Registered

2021-09-18

Start date

2021-07-06

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease. Atherosclerotic heart disease of native coronary artery

Interventions

Intervention 1: Intervention group: 1. Lavender" Patients of the experimental group (lavender group) After complaining of headache, lavender essential oil 1.5% prepared by Kazerun Agro-industrial Co

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: No previous history of nitrate use no history of allergies no use of painkillers 6 hours before the intervention no headache before the intervention no use of perfume or cologne before or during the intervention No history of drug addiction according to the patient no olfactory disorder according to the patient

Exclusion criteria

Exclusion criteria: Withdrawal from the study having a headache before the infusion of nitroglycerin decreased level of consciousness during the study allergies caused by the essential oils of valerian and lavender or herbal essences during the study

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: manometer.;Drug use following the inhalation of fragrance and its effect on headache The need for narcotics changes based on the visual pain scale. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Visual Analogue Scale.;Heart rate. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Heart rate monitoring device.;Temperature. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Mercury thermometer.;Respiratory Rate. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Count the number of breaths per minute based on chest movements while breathing.;Percentage of blood oxygen saturation. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: pulse oximetry.	—

Measure

Time frame

Blood pressure. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: manometer.;Drug use following the inhalation of fragrance and its effect on headache The need for narcotics changes based on the visual pain scale. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Visual Analogue Scale.;Heart rate. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Heart rate monitoring device.;Temperature. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Mercury thermometer.;Respiratory Rate. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Count the number of breaths per minute based on chest movements while breathing.;Percentage of blood oxygen saturation. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: pulse oximetry.

—

Secondary

Measure	Time frame
Pain. Timepoint: 30 minutes (before the intervention and 15, 30). Method of measurement: Visual Analogue Scale (VAS ).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeili Yekefallah

Qazvin University of Medical Sciences

leili_fallah@yahoo.com+98 28 3333 8034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026