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Comparison of Viola odorata and Budesonide in Reducing Airway Inflammation by Ultrasound and Cuff Leak Test

Comparison of Viola odorata and Budesonide in Reducing Airway Inflammation in intubated patients by Ultrasound and Cuff Leak Test

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210516051314N1
Enrollment
60
Registered
2021-06-09
Start date
2021-06-10
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tracheal inflammation.

Interventions

Intervention 1: Intervention group: salbutamol 2.5 mg with nebulizer four times per day and viola odorata syrup 10 cc three times a day from first day on intubation till seven days after intubation.

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 65 years old intubation due to trauma intubation atleast for 24 hours and during past 2 weeks ongoing need for intubation

Exclusion criteria

Exclusion criteria: Failure to continue treatment for any reason, including the reluctance of the patient or the patient's caretaker drug intolerance tracheomalacia or any other airway disease obesity hypoventilation syndrome or any other lung disease inhaled or systemic corticosteroids usage in previous month need for systemic corticosteroid administration in current addmision hemodynamic instability smoking 25 cigarettes per day or more

Design outcomes

Primary

MeasureTime frame
Air column diameter between tracheal tube and tracheal wall. Timepoint: First and 7th day after intubation. Method of measurement: Ultrasound.;Tracheal wall thickness. Timepoint: First and 7th day after intubation. Method of measurement: Ultrasound.;Volume of air leak around tracheal tube. Timepoint: First and 7th day after intubation. Method of measurement: Expiratory tidal volume difference when the endotracheal tube cuff is full and empty and measured by a ventilator.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Soltanmohammadi

Esfahan University of Medical Sciences

sara.sm.68@gmail.com+98 21 6655 7772

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026