Anesthetic efficacy of two different volumes of articaine for mental nerve block

Comparative evaluation of anesthetic efficacy of 1.8 mL articaine and 3.6 mL of articaine for mental nerve block in mandibular premolars with irreversible pulpitis: A randomized clinical trial study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210515051306N2

Enrollment

Registered

2023-04-24

Start date

2022-12-01

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

irreversible pulpitis of the mandibular premolar. k04.0

Interventions

Intervention 1: Intervention group: The mental nerve block involved a deposition of 1.8 mL 4% articaine with1:100,000 epinephrine (Artinibsa, Inibsa, Barcelona, Spain) each patient received a cartridg

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Healthy adult patients 18–60 years old Having a mandibular premolar tooth with symptomatic irreversible pulpitis Normal periapical radiographic appearance

Exclusion criteria

Exclusion criteria: History of sensitivity to 4%articaine or epinephrine Systemic diseases Pregnancy or breastfeeding Any type of medication that could potentially interact with the anesthetic solution Spontaneous pain Periodontal disease or unable to get restoration Having pain killer late 12 hours

Design outcomes

Primary

Measure	Time frame
Pain score during treatment on Visual Analogue Scale (VAS). Timepoint: before administration of the anesthetic solution and during the endodontic treatment. Method of measurement: Visual Analogue Scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRamin Abazarpoor

Rafsanjan University of Medical Sciences

ram_aba@yahoo.com+98 34 3428 0031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026