anesthetic efficacy of 1.8 mL articaine, 1.8 mL and 3.6 mL of lidocaine for mental nerve block in irreversible pulpitis of the mandibular premolar

Comparative evaluation of anesthetic efficacy of 1.8 mL articaine, 1.8 mL and 3.6 mL of lidocaine for mental nerve block in mandibular premolar with irreversible pulpitis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210515051306N1

Enrollment

165

Registered

2021-07-07

Start date

2021-06-22

Completion date

Unknown

Last updated

2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

irreversible pulpitis of the mandibular premolar. Pulpitis

Interventions

Intervention 1: 1st Intervention group: The mental nerve block involved adeposition of 1.8 mL 2% lidocaine with1:80,000 epinephrine (Xilonibsa, Inibsa, Barcelona, Spain) each patient received 2 cartri

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Healthy adult patients 18–60 years old Having a mandibular premolar tooth with symptomatic irreversible pulpitis Normal periapical radiographic appearance

Exclusion criteria

Exclusion criteria: History of sensitivity to 4%articaine or epinephrine Systemic diseases Pregnancy or breastfeeding Any type of medication that could potentially interact with the anesthetic solution Spontaneous pain Periodontal disease or unable to get restoration Having pain killer late 12 hours

Design outcomes

Primary

Measure	Time frame
Pain score during treatment on Visual Analogue Scale (VAS). Timepoint: before administration of the anesthetic solution and during the endodontic treatment. Method of measurement: Visual Analogue Scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRamin Abazarpoor

Rafsanjan University of Medical Sciences

ram_aba@yahoo.com+98 34 3428 0031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026