A comparison between the effectiveness of two different oral pastes, containing Triamcinolone and Rhus Coriaria on minor aphthous lesions: a triple blind randomized clinical trial

A comparison between the effectiveness of two different oral pastes, containing Triamcinolone and Rhus Coriaria on patients with minor oral aphthous lesions: a triple blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210513051281N1

Enrollment

Registered

2021-09-17

Start date

2021-08-30

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Oral aphthae. Recurrent oral aphthae

Interventions

Intervention 1: Intervention group: Patients in the intervention group receive a drug containing the sumac (Rhus Coriaria) active ingredient. They should apply the gel on the aphthous lesion 3 times a

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients with minor aphthous lesions who have visited within the first 24 hours of incidence of the lesion. Patient does not have any systemic disease ( Hypertension, Diabetes, Hyperlipidemic, Bechet's disease, Rheumatoid disease) Do not use medicines, cigarettes', alcohol and addiction.

Exclusion criteria

Exclusion criteria: Patients allergic to herbal medicines Oral ulcers that are not aphthous lesions. More than 48hrs passed from incidence of the lesion. Use of medicines, cigarettes', alcohol and addiction. Systemic diseases.

Design outcomes

Primary

Measure	Time frame
Size. Timepoint: First day, third day, fifth day and seventh day after they start taking the medicine. Method of measurement: dental probe instrument.;Pain. Timepoint: First day, third day, fifth day and seventh day after they start taking the medicine. Method of measurement: On study days, the patient is asked to mark from zero to ten on visual analog scale(VAS).;Healing duration. Timepoint: First day, third day, fifith day and seventh day after they start taking the medicine. Method of measurement: visual examination.	—

Measure

Time frame

Size. Timepoint: First day, third day, fifth day and seventh day after they start taking the medicine. Method of measurement: dental probe instrument.;Pain. Timepoint: First day, third day, fifth day and seventh day after they start taking the medicine. Method of measurement: On study days, the patient is asked to mark from zero to ten on visual analog scale(VAS).;Healing duration. Timepoint: First day, third day, fifith day and seventh day after they start taking the medicine. Method of measurement: visual examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mahdie Zarabadipour

Qazvin University of Medical Sciences

mzarabadipour@qums.ac.ir+98 28 3335 3009

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026