Thin peri-implant soft tissue thickness.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Thin vertical sot tissue thickness(less than 2 mm) 4 mm keratinized tissue at least Partial edentulus in posterior of jaws Healthy soft tissue
Exclusion criteria
Exclusion criteria: Need to bone augmentation procedure O’ LEARY plaque index more than 20% Tobacco consumption Systemic disease related to soft & hard tissue healing Drug consumption related to soft & hard tissue healing Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Soft tissue thickness. Timepoint: Base line, 2 months. Method of measurement: The thickness of the soft tissue in the center of the implant will be measured with a UNC periodontal probe (Hu-Friedy, USA) relying on the lingual flap.;Amount of collagen. Timepoint: Base line, 2 months. Method of measurement: The biopsy specimens will be placed in paraffin blocks after fixation and microscopic incisions 3-4 mm thick will be prepared. The prepared sections will then be stained with Masson trichrom to evaluate the amount of collagen.;Inflammation rate. Timepoint: Base line, 2 months. Method of measurement: Biopsy specimens are stained with hematoxylin-eosin to measure the severity of inflammation and will be classified to mild, moderate, and severe.;Vascular density. Timepoint: Base line, 2 months. Method of measurement: Immunohistochemical staining with CD34 monoclonal antibody prepared from mice will be used to evaluate blood vessels. | — |
Countries
Iran (Islamic Republic of)
Contacts
Islamic Azad University