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Comparison of clinical course of the disease in patients with Covid-19 infection with or without antibiotics

Comparison of clinical course of the disease in patients with Covid-19 infection with or without antibiotics

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210510051248N1
Enrollment
90
Registered
2022-01-22
Start date
2022-01-21
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19. COVID-19, virus identified

Interventions

Intervention 1: Intervention group: Vial Remdesivir 100 mg Ronak Pharmaceutical Company for 5 days, 200 mg on the first day and 100 mg on the second to fifth days
Levofloxacin 750 mg tablets Abidi Pharmaceutical Company for 5 days, 750 mg daily
Vial Ceftriaxone 1 gr Exir Pharmaceutical for 5 days, 1 gr every 12 hours
. Intervention 2: Control group: Vial Remdesivir 100 mg Ronak Pharmaceutical Company for 5 days, the first day 200 mg and the second to fifth days 100 mg.

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Patients with confirmed molecular test (PCR positive) Blood oxygen saturation level SpO2 <93% in room air Patients with moderate pulmonary involvement in radiological studies No need for antibiotics in terms of indicator bacterial infection (PCT negative)

Exclusion criteria

Exclusion criteria: Patient dissatisfaction with participation in the study Need for antibiotics according to the indication of bacterial infection (PCT positive)

Design outcomes

Primary

MeasureTime frame
Erythrocyte Sedimentation rate. Timepoint: Measurement of erythrocyte sedimentation rate on the first and seventh days. Method of measurement: Measurement of erythrocyte sedimentation rate by the device ESR analyzer semimex.;C-reactive protein. Timepoint: Measurement of C-reactive protein on the first and seventh days. Method of measurement: Measurement of C-reactive protein with the device BT-3500 And BT-3000.;Ferritin. Timepoint: Measurement of ferritin on the first and seventh day. Method of measurement: Measurement of ferritin with the device Cobas.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Raesi

Shahre-kord University of Medical Sciences

raesi.a@skums.ac.ir+98 38 3222 0016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026