Evaluation of the relationship between end tidal carbon dioxide pressure and the incidence of severe nausea and vomiting after general anesthesia in laparoscopic cholecystectomy.
Conditions
Interventions
Intervention 1: Intervention group: The first group of people undergoing laparoscopic cholecystectomy, which is maintained by a capnograph of the end-tidal carbon dioxide level between 35-40 mm Hg. In
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 88 candidates for laparoscopic cholecystectomy with ASA1,2 in the age group of 18-65 years
Exclusion criteria
Exclusion criteria: Patients with ASA 3 and 4 Severe underlying disease such as heart failure, COPD, ESRD History of motion sickness and history of postoperative nausea and vomiting Allergy to anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determining and comparing the frequency of postoperative nausea and vomiting in two groups with expiratory end carbon dioxide pressure of 40-40 and 40-45. Timepoint: Every 15 minutes in recovery 2, 4 and 6 hours after surgery. Method of measurement: Through a questionnaire.;Determining and comparing the average dose of antiemetic drugs in two groups with expiratory carbon dioxide pressure of 40-40 and 45-40. Timepoint: At recovery time 2, 4 and 6 hours after surgery. Method of measurement: Through a questionnaire.;Determining and comparing the average dose of opioids in two groups with expiratory end carbon dioxide pressure of 35-40 and 40-45. Timepoint: At recovery time 2, 4 and 6 hours after surgery. Method of measurement: Through a questionnaire.;Determination and comparison of pain intensity during recovery in two groups with expiratory end of carbon dioxide pressure of 35-40 and 40-45. Timepoint: 2, 4 and 6 hours after surgery. Method of measurement: Based on VAS.;Determining and comparing the average level of patient satisfaction in two groups with expiratory end carbon dioxide pressure of 40-40 and 45-40. Timepoint: In 6 hours after surgery. Method of measurement: Based on VAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Determination and comparison of mean arterial blood pressure, oxygen saturation and heart rate in two groups with expiratory end carbon dioxide pressure of 40-40 and 45-40. Timepoint: Basically then every half hour during surgery and recovery. Method of measurement: Through a questionnaire.;Determining and comparing the duration of anesthesia and the duration of recovery surgery (duration of extubation) in two groups with expiratory end carbon dioxide pressure of 35-40 and 40-45. Timepoint: end of surgery. Method of measurement: Through a questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Khosro Naghibi
Esfahan University of Medical Sciences
Outcome results
None listed