Chronic heart Failure. Heart failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Class II and III heart failure based on NYHA criteria Having suffered from heart failure for the past 3–5 years Clinical status and stable hemodynamics at least one month before entering the study Ejection fraction less than 50% based on echocardiography Being treated with standard medication Age range: 50 to 70 years
Exclusion criteria
Exclusion criteria: Unstable angina and complex ventricular arrhythmias The occurrence of myocardial infarction in the past year having pacemaker During the last six months, have bypass surgery or angioplasty. Participate in other exercise programs six months before the start of the study. The existence of musculoskeletal disorders that prevent normal walking Existence of cognitive disorders Lack of personal desire to cooperate History of lung disease, smoking, angina, heart attack or heart surgery (less than six months), orthopedic or neurological diseases, steroid therapy, or chemotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The basic rate of respiration. Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: Average rate of five minutes of respiration based on respirometer biofeedback.;Inflammation. Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: According to the report of TNF-alpha in an enzyme-linked immunosorbent assay device.;Heart Rate Variability. Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: Holter monitoring device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life. Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: Minnesota Quality of Life Questionnaire Score.;Cholesterol. Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: Based on an autoanalyzer device's report from a person's blood serum.;Triglyceride. Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: From a person's blood serum based on the report of an autoanalyzer device.;High-Density Lipoprotein (HDL). Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: From a person's blood serum based on the report of an autoanalyzer device.;Low-Density Lipoprotein (LDL). Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: From a person's blood serum based on the report of an autoanalyzer device.;Systolic blood pressure at rest. Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: According to the average Holter blood pressure report.;Diastolic blood pressure at rest. Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: According to the average Holter blood pressure report.;Rate of perceived exertion. Timepoint: 48 hours before and after the six-minute walk test and 48 hours after the end of four weeks of intervention before and after the six-minute walk test. Method of measurement: Based on the Borg scale.;Standard Deviation of NN Intervals (SDNN). Timepoint: 48 hours before the intervention and 48 hours after the end of four weeks of intervention. Method of measurement: According to the report of the cardiac Holter device.;Root Mean Square of Successive Differen | — |
Countries
Iran (Islamic Republic of)
Contacts
Tarbiat Modares University