The effect of combined rehabilitation exercises in patients with coronary artery bypass grafting

The effect of a combined training session on ABCA5 and ApoB gene expression and white blood cell lipid profile in middle-aged men after cardiac bypass surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210426051087N1

Enrollment

Registered

2021-06-11

Start date

2020-04-20

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic ischaemic heart disease, unspecified. Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris

Interventions

Intervention 1: Intervention group: Aerobic-resistance training group. After taking blood samples and functional tests (5-second unassisted sit-up test (TUG), 3-meter back and forth (BBS) and cardiore

Eligibility

Sex/Gender

Male

Age

50 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age range 50-60 years Willingness to participate in research Cognitive, visual and auditory health No systolic blood pressure higher than 160 mmHg and diastolic blood pressure higher than 100 mmHg No acute and advanced diseases that prevent the exercises considered in this study.

Exclusion criteria

Exclusion criteria: Existence of symptoms and heart failure Taking over-the-counter medications Inability to perform sports activities

Design outcomes

Primary

Measure	Time frame
ABCG5 gene expression. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: REAL TIME-PCR method.;APOB plasma levels. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: ELISA laboratory method.;LDL plasma levels. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: ELISA laboratory method.	—

Measure

Time frame

ABCG5 gene expression. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: REAL TIME-PCR method.;APOB plasma levels. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: ELISA laboratory method.;LDL plasma levels. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: ELISA laboratory method.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Amir Rashid Lamir

Islamic Azad University

m_akbari64@hotmail.com+98 51 3880 3000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026