The effect of simvastatin 2% ointment on bed sores

The assesment of the effect of topical simvastatin 2% ointment in patients with bedsore grade 1,2: A randomized controlled clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210423051047N1

Enrollment

104

Registered

2021-05-16

Start date

2021-06-06

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Stage I Bedsore. Condition 2: Stage II Bedsore. Stage I decubitus ulcer and pressure area Stage II decubitus ulcer

Interventions

Intervention 1: The intervention group consisted of 52 patients with grade 1 and 2 bed sores who were treated with simvastatin 2% ointment (as daily) prepared in the laboratory of the Islamic Azad Sch

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with grade 1 and 2 bed sores

Exclusion criteria

Exclusion criteria: Patients with severely infected wounds or a high risk of infection. Patients whose length of hospital stay is less than 14 days. Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
Reducing wound size. Timepoint: 7 and 14 days after the intervention. Method of measurement: Ruler.	—

Secondary

Measure	Time frame
Reduce the length of hospital stay. Timepoint: Daily after intervention. Method of measurement: Observational.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayyeh Nasiripour

Iran University of Medical Sciences

nasiripours@yahoo.com+98 21 6655 8811

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026