The effect of pomegranate peels extract on clinical symptoms of patients with irritable bowel syndrome

The Effect of Pomegranate peel extract on clinical symptoms ,stool calprotectin level and quality of life in patients with diarrhea-dominant irritable bowel syndrome : A double-blind randomized placebo-controlled clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210423051046N1

Enrollment

Registered

2022-01-05

Start date

2021-05-31

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable bowel syndrome. Irritable bowel syndrome

Interventions

Intervention 1: Intervention group: This group, which consisting of 31 patients with irritable bowel syndrome and randomly selected, will receive two 250 mg capsules containing pomegranate peel extrac

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Irritable bowel syndrome patients with diarrhea dominant symptom

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Score of clinical symptoms in first questionnaire. Timepoint: Before the intervention and 2 months after the beginning of intervention. Method of measurement: The second questionnaire.;Stool calprotectin level. Timepoint: Before the intervention and 2 months after the beginning of intervention. Method of measurement: Measured by the laboratory.;Quality of life. Timepoint: Before the intervention and 2 months after the beginning of intervention. Method of measurement: Quality of Life Questionnaire for Patients with Irritable Bowel Syndrome.	—

Measure

Time frame

Score of clinical symptoms in first questionnaire. Timepoint: Before the intervention and 2 months after the beginning of intervention. Method of measurement: The second questionnaire.;Stool calprotectin level. Timepoint: Before the intervention and 2 months after the beginning of intervention. Method of measurement: Measured by the laboratory.;Quality of life. Timepoint: Before the intervention and 2 months after the beginning of intervention. Method of measurement: Quality of Life Questionnaire for Patients with Irritable Bowel Syndrome.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Javan Ali Azar

Tabriz University of Medical Sciences

Fateme.javan88@gmail.co+98 41 3320 1309

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026