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Effect of Organosulfur Compounds on COVID-19 patients

Effect of oral Organosulfur Compounds as adjuvant therapy on patients Hospitalized with COVID-19: A phase III, multicenter and double-blind randomized placebo-controlled clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210422051044N1
Enrollment
60
Registered
2021-05-28
Start date
2021-07-06
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. U07.1

Interventions

Intervention 1: Control group: Positive PCR patients referred to Bushehr Persian Gulf Hospital who received placebo. Intervention 2: Intervention group: PCR positive patients referred to Bushehr Persi

Sponsors

NICOVIDEO Research Company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Participants age are within 18-70 years Participants should not be pregnant or Breastfeeding Participants who not ventilator dependence

Exclusion criteria

Exclusion criteria: History of allergy to Organosulfur Compounds History of allergies to garlic and onions The patient has a history of hypotension The patient has a history of Gastrointestinal bleeding hypotension at the beginning of the study (below 120/80) The patient has a history immunodeficiency diseases The inability of the patient to swallow the oral medication or via NG tube

Design outcomes

Primary

MeasureTime frame
Primary outcomes including clinical signs, lymphocyte percentage, LDH, SpO2, CRP, CBC. Timepoint: At baseline then 10 days from initiated time. Method of measurement: Information of hospitalized patients through direct examination and information entered in the file and patients who are discharged are referred to the clinic on an outpatient basis on the tenth day.

Secondary

MeasureTime frame
Lymphocytopenia. Timepoint: Before starting the study, 10 days later. Method of measurement: Cell Counter (CBC).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamed Gholizade

Boushehr University of Medical Sciences

gholizadeh7575@gmail.com+98 77 4111 8334

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026