Evaluation of the effects of solution made with flax seed oil in the treatment of rhinosinusitis

Evaluation of the effects of topical application of micro emulsion prepared with Flax seed oil carrier of lipophilic active ingredients in the treatment of inflammatory disorders of rhino sinus cavity

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210421051030N1

Enrollment

Registered

2021-08-13

Start date

2021-08-14

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Rhinitis. Condition 2: Sinusitis. Allergic rhinitis, unspecified Acute sinusitis, unspecified

Interventions

Intervention 1: Control group: Patients are treated with oral tablets (single dose of co amoxiclav 325 mg per day in bacterial rhinosinusitis and fexofenadine 180 in allergic rhinosinusitis). They als

Eligibility

Sex/Gender

All

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: All Rhinosinusitis patients over 15 years of age and under 60 years of age Not used immunosuppressive and antibiotics drugs during the last week Not allergic to herbal medicines and topical products No systemic diseases involving the Nasal cavity and Sinuses

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Inflammation of the mucosa of the rhino sinus cavity. Timepoint: Before the intervention, after the intervention, one week after the intervention. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Headache. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Pressure and capillaries (the nose and paranasal sinuses). Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Sputum secretions. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Itching and runny nose. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Congestion and olfactory disorder. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Fever, cough and phlegm. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Swelling of the mucosa. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Examination.;Redness of the mucosa. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Examination.;Mucosal lesions. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Examination.;Mucosal ulcers. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Examination.	—

Measure

Time frame

Headache. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Pressure and capillaries (the nose and paranasal sinuses). Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Sputum secretions. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Itching and runny nose. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Congestion and olfactory disorder. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Fever, cough and phlegm. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Questionnaire (Based on patient self-expression).;Swelling of the mucosa. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Examination.;Redness of the mucosa. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Examination.;Mucosal lesions. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Examination.;Mucosal ulcers. Timepoint: Before the intervention, one week after the intervention. Method of measurement: Examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehnam Mokri Savojbolaghi

Iran University of Medical Sciences

bms1909@iran.ir+98 21 0000 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026