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A Comparison of the effect of dexmedetomidine and remifentanil on analgesia and respiratory parameters in patients undergoing stereotactic brain biopsy

A Comparison of the effect of dexmedetomidine and remifentanil on analgesia and respiratory parameters in patients undergoing stereotactic brain biopsy

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210415050983N2
Enrollment
40
Registered
2022-01-09
Start date
2021-12-22
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stereotactic biopsy.

Interventions

Intervention 1: First, under local anesthesia of the scalp with 20 cc of 1.5% lidocaine and 50 micrograms of intravenous fentanyl, a stereotactic form is installed for the patient and the patient is t

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients 18-50 years old candidate for stereotactic Patients with supratentorial lesions with or without hydrocephalus No dysfunction of the liver and kidneys No drug addiction Consent to participate in the study

Exclusion criteria

Exclusion criteria: BMI >35 or<16 mental disorder Uncontrolled epilepsy Alcohol and drug abuse Having a comorbid condition such as high blood pressure History of chronic pain Patients with brainstem lesions Intubated patients

Design outcomes

Primary

MeasureTime frame
Hemodynamic parameters. Timepoint: Every 5 minutes from the moment you enter the operating room. Method of measurement: monitoring.;Respiratory parameters. Timepoint: Every 5 minutes from the moment you enter the operating room. Method of measurement: monitoring.;Seadation. Timepoint: Every 5 minutes from the moment you enter the operating room. Method of measurement: Ramssy Criteria.;Analgesia. Timepoint: Every 5 minutes from the moment you enter the operating room. Method of measurement: VAS criteria.;Recovery from sedation. Timepoint: Every 10 minutes after the procedure. Method of measurement: Aldert criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSogol Asgari

Shahid Beheshti University of Medical Sciences

drasgari98429@gmail.com+98 21 5541 9005

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jul 25, 2026